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Introducing Coretox: A Revolutionary Advancement in Toxin Therapy
Coretox represents a pioneering leap in the world of toxin-based pharmaceuticals, standing as the second toxin drug globally to feature a neurotoxin of 150kDa. This breakthrough was achieved by meticulously eliminating non-toxin proteins, a common cause of resistance, from the pre-existing 900kDa toxin drug. Notably, this innovation addresses a critical need, significantly minimizing resistance concerns.
Innovative Formulation and Benefits
Coretox is engineered to temporarily enhance moderate to severe glabellar wrinkles associated with muscle activity, particularly the corrugator and procerus muscles. These improvements are observed in adults ranging from 20 to 65 years of age. Moreover, Coretox proves highly effective in the treatment of upper limb spasticity in adult patients aged 19 and above.
Available as a lyophilized white powder for injection, Coretox comes in a colorless transparent vial. Upon dissolution with saline, it transforms into a clear, transparent solution ready for administration. Its distinct composition excludes animal-derived components in both the toxin culture media and the end product of HSA, marking Coretox as a unique 150kDa botulinum toxin product.
Immunogenicity and Safety Considerations
An essential aspect of toxin-based treatments is understanding immunogenicity, as excessive absorption of botulinum toxin can elevate the risk of antibody formation. Coretox® addresses this concern by being the world's first 150kDa botulinum toxin product devoid of animal-derived components, aligning with evolving preferences to avoid human or animal proteins during drug manufacturing.
To ensure its stability and effectiveness, it is recommended to store the unopened lyophilized vial of Coretox in a refrigerator at a temperature of 2~8°C.
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