Revofil Aquashine BTX

Revofil Aquashine BTX is an advanced injectable skin rejuvenation treatment developed by Caregen, a South Korean biotechnology company internationally recognized for its research and development of biomimetic peptides.

Unlike traditional dermal fillers that primarily restore volume, Aquashine BTX is positioned as a skin booster with peptide-based bio-restructuring properties. It combines non-crosslinked hyaluronic acid with a high concentration of functional peptides and supportive nutrients to improve hydration, elasticity, wrinkle depth, and overall skin quality.

The “BTX” designation refers to its botulinum toxin–like (Botox-like) peptide activity, meaning it provides a mild muscle-relaxing effect without containing actual botulinum toxin.

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1. Product Overview

• Type: Injectable mesotherapy / skin booster

• Primary Indications: Fine lines, early wrinkles, dehydration, skin laxity, dull complexion, pigmentation irregularities

• Injection Depth: Epidermal to superficial/mid-dermis

• Manufacturer: Caregen (South Korea)

• Intended Users: Licensed medical professionals

Aquashine BTX is commonly used in aesthetic medicine as part of anti-aging protocols for patients seeking natural-looking rejuvenation rather than volumization.

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2. Key Ingredients & Mechanism of Action

The product’s efficacy is based on a synergistic combination of hyaluronic acid, biomimetic peptides, and supportive nutrients.

A. Non-Crosslinked Hyaluronic Acid (15 mg/ml)

• Provides intense hydration by binding water molecules

• Improves skin turgor and elasticity

• Enhances transdermal nutrient diffusion

• Supports temporary dermal plumping

Unlike cross-linked fillers, this HA is not designed to create volume but to improve skin quality and hydration.

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B. Biomimetic Peptide Complex

Caregen specializes in synthetic peptides that mimic naturally occurring signaling molecules in the body. These peptides act on specific skin pathways:

1. Muscle-Relaxing (“BTX-like”) Peptides

• Decapeptide-29

• Oligopeptide-62

These peptides may modulate neuromuscular signaling, helping to soften dynamic wrinkles (e.g., forehead lines, crow’s feet) by reducing excessive muscle contraction — similar in concept to botulinum toxin, but significantly milder and temporary.

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2. Collagen & Elastin Stimulating Peptides

• Acetyl Decapeptide-3

• Oligopeptide-24

• Oligopeptide-72

These peptides promote fibroblast activity and stimulate synthesis of:

• Collagen

• Elastin

• Extracellular matrix components

This contributes to:

• Improved firmness

• Increased dermal density

• Gradual lifting effect

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3. Brightening & Anti-Pigmentation Peptides

• Oligopeptide-34

• Oligopeptide-51

These target melanogenesis by helping regulate melanin production, contributing to:

• Reduced hyperpigmentation

• More even skin tone

• Enhanced radiance

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C. Additional Bioactive Components

Aquashine BTX contains over 50 supportive ingredients including:

• Amino acids (structural support for collagen)

• Vitamins (antioxidant protection)

• Minerals (cellular metabolism support)

• Coenzymes (cell regeneration support)

Together, these contribute to:

• Oxidative stress reduction

• Skin repair stimulation

• Improved barrier function

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3. Clinical Benefits

1. Wrinkle Reduction

The combination of hydration and peptide-induced muscle modulation helps:

• Soften fine lines

• Reduce dynamic wrinkles

• Improve nasolabial folds appearance

• Smooth forehead and periocular lines

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2. Deep & Long-Lasting Hydration

Hyaluronic acid increases water retention within the dermis, resulting in:

• Plumper skin

• Improved elasticity

• Reduction of crepey texture

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3. Skin Rejuvenation & Lifting

By stimulating collagen and elastin production, Aquashine BTX:

• Enhances firmness

• Improves skin density

• Provides subtle tightening

• Delays visible aging progression

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4. Brightening & Tone Correction

Targeted peptides help:

• Reduce pigmentation irregularities

• Improve dull complexion

• Promote luminous, even skin tone

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5. Minimally Invasive with Limited Downtime

• Delivered via microinjections

• Mild redness or swelling typically resolves within 24–72 hours

• No surgical intervention required

Results typically become noticeable within 1–2 weeks, with progressive improvement over several months.

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4. Treatment Protocol

Administration

• Performed by a qualified medical professional

• Injected into epidermal to superficial/mid-dermal layers

• Micro-papular mesotherapy technique commonly used

Pain Management

• Topical anesthetic cream applied 20–30 minutes prior

• Procedure generally well tolerated

Standard Course

• Initial phase: 3 sessions

• Interval: 3–4 weeks apart

Maintenance

• 2–3 sessions per year

• Effects may last up to 10–12 months depending on:

  • Age

  • Skin condition

  • Lifestyle

  • Metabolic rate

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5. Ideal Candidates

• Patients aged 25+ with early signs of aging

• Individuals with dehydrated or dull skin

• Patients seeking prevention rather than heavy correction

• Those wanting mild wrinkle reduction without full neurotoxin treatment

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6. Safety & Considerations

• Must be administered by trained professionals

• Contraindications include:

  • Pregnancy and breastfeeding

  • Active skin infections

  • Autoimmune conditions (case-dependent)

  • Known hypersensitivity to ingredients

Side effects are typically mild and temporary:

• Swelling

• Bruising

• Redness

• Tenderness

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7. How It Differs from Traditional Fillers & Botox

Feature	Aquashine BTX	Traditional HA Fillers	Botulinum Toxin
Adds volume	Minimal	Yes	No
Hydrates	Yes	Moderate	No
Muscle relaxation	Mild (peptides)	No	Strong
Collagen stimulation	Yes	Limited	No
Downtime	Minimal	Minimal	Minimal

Aquashine BTX occupies a hybrid category: part skin booster, part regenerative therapy, with a soft neuromodulating component.

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Conclusion

Revofil Aquashine BTX represents a multi-mechanism anti-aging solution combining hydration, peptide-based regeneration, mild wrinkle relaxation, and pigmentation control in a single formulation. Developed by Caregen, it reflects the growing trend toward bioactive skin rejuvenation rather than simple volumization.

It is particularly suitable for patients seeking:

• Natural-looking enhancement

• Improved skin quality

• Preventative anti-aging care

• Subtle wrinkle softening without traditional Botox