Frequently bought together
Introducing Coretox: A Revolutionary Advancement in Toxin Therapy
Coretox represents a pioneering leap in the world of toxin-based pharmaceuticals, standing as the second toxin drug globally to feature a neurotoxin of 150kDa. This breakthrough was achieved by meticulously eliminating non-toxin proteins, a common cause of resistance, from the pre-existing 900kDa toxin drug. Notably, this innovation addresses a critical need, significantly minimizing resistance concerns.
Innovative Formulation and Benefits
Coretox is engineered to temporarily enhance moderate to severe glabellar wrinkles associated with muscle activity, particularly the corrugator and procerus muscles. These improvements are observed in adults ranging from 20 to 65 years of age. Moreover, Coretox proves highly effective in the treatment of upper limb spasticity in adult patients aged 19 and above.
Available as a lyophilized white powder for injection, Coretox comes in a colorless transparent vial. Upon dissolution with saline, it transforms into a clear, transparent solution ready for administration. Its distinct composition excludes animal-derived components in both the toxin culture media and the end product of HSA, marking Coretox as a unique 150kDa botulinum toxin product.
Immunogenicity and Safety Considerations
An essential aspect of toxin-based treatments is understanding immunogenicity, as excessive absorption of botulinum toxin can elevate the risk of antibody formation. Coretox® addresses this concern by being the world's first 150kDa botulinum toxin product devoid of animal-derived components, aligning with evolving preferences to avoid human or animal proteins during drug manufacturing.
To ensure its stability and effectiveness, it is recommended to store the unopened lyophilized vial of Coretox in a refrigerator at a temperature of 2~8°C.
Frequently asked questions
Brunodermafiller is committed to offering you the most competitive prices. Depending on the products and quantities you purchase, you can save up to 20% compared to other distributors.
Due to the high-risk classification of Botox, many standard payment providers do not support transactions for these products. As a result, we do not accept card payments, Apple Pay, or PayPal. All payments are made via bank transfer only.
Here’s how it works: Once you place your order, you’ll receive bank transfer details based on the currency you choose sent securely via email within 24 hours. Please check your spam, junk, or promotions folder if you don’t see it. If it’s still missing, feel free to contact our support team and we’ll resend it promptly.
Payment instructions are sent via email within 24 hours of placing your order. If you haven’t received them, please check your spam, junk, or promotions folder—it’s often filtered there. Still nothing? Contact our support team and we’ll make sure you get them right away.
In rare cases, depending on your country’s customs regulations and current events, additional custom fees might apply at delivery. These are unfortunately outside of our control and vary by region. Most of our customers don’t encounter extra charges, but if it does happen, we just want you to be aware of them in advance. We’re always here to help if anything comes up.
In some cases, certain banks may charge a small fee for international payments. While this isn’t something we control (and we never add fees ourselves), we don’t want you to feel that cost is coming out of your own pocket. It also isn’t the quickest or most convenient,and while it’s not ideal, we really appreciate you going through it. That’s why we offer you a small gift upon reaching checkout. You’ll get to choose from a selection of free products to thank you for your order and make sure you’re still getting full value. It’s our way of showing you that your effort doesn’t go unnoticed.
- USA, Canada, Japan: 2–5 business days
- Europe (excluding Germany and Italy): 3–5 business days
- Germany & Italy: 3–6 business days (tracking number available after 2 days)
- South Africa: 7+ business days
- Dominican Republic: 8–12 business days
- Reunion: 3–6 business days
Delays may occur because of customs clearance or flight schedules.
For aesthetic treatment products (like injectables), we use temperature-controlled packaging when required, following safety and hygiene standards.Discreet packaging is used by default- no product names are displayed on the outside.
To modify or cancel your order, please contact us as soon as possible at info@brunodermalfiller.com.If your order hasn’t been processed or shipped yet, we’ll do our best to accommodate your request. Once it’s been dispatched, changes or cancellations are no longer possible, but you may be eligible for a return or exchange after delivery
